Ok so to quickly cover the basics, water meth or meth injection is a chemical additive to the intake stream used to cool intake air temps. It alows for advanced timing, higher compression, higher boost levels and some other goodies. It basically increases the octane level at the same time. Its more popular in boosted applications since it makes engines handle boost levels on pump gas that would otherwise be unsafe for the motor.
Now lets get into what I'm looking at.
I've installed a water meth kit on Sarahs G5 (2.2L ecotec with eaton M62 roots style super charger). Im getting ready to tune it in and looking for experience from other people. I know that the meth changes the stoich for the fuel mixture since pure alcohol runs at close to 4:1 vs the 14.6 the gas wants to be at. The fuel maps on the car are going to have to be pulled back a bit so i dont over fuel the car. The nozzle size and the mix is where the room to play is. Most cobalts with meth are running 5gph nozzles with a 50/50 mix. Its my understanding that this is the "general best" and not the actual best. From watching other twin screw/roots style blowers, they eat up WAY more meth than NA or turbo cars. Thats simply because the massive surface area of the blower itself. They also tend to evaporate a bunch of meth (when running pure meth) prior to it making its way into the cylinder. People who are tuning their methanol kits on dynos and doing some pretty serious playing around with them (still using the same style blowers) tend to notice the best gains with a bit of water mixed in, just so the mix makes it all the way to the combustion chamber.
Thats what I have noticed and some of the people who I've talked to running similar set ups (granted a lightning and a kenny bell explorer are a bit different) have noticed as well. I also had a lengthy conversation with two different manufacturers to get their inputs. Now I'm looking to hear from others who have gotten down and dirty with this stuff. I will also update this thread more info for this kind of tuning